Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113888 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
Runt-related transcription factor 1
Molecule details ›
Chains: A, C
Length: 134 amino acids
Theoretical weight: 14.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Runt domain
Structure domains: Immunoglobulin-like
Length: 134 amino acids
Theoretical weight: 14.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q01196 (Residues: 50-183; Coverage: 30%)
Sequence domains: Runt domain
Structure domains: Immunoglobulin-like
Core-binding factor subunit beta
Molecule details ›
Chains: B, D
Length: 134 amino acids
Theoretical weight: 15.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Core binding factor beta subunit
Structure domains: Core binding factor, beta subunit
Length: 134 amino acids
Theoretical weight: 15.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q13951 (Residues: 2-135; Coverage: 74%)
Sequence domains: Core binding factor beta subunit
Structure domains: Core binding factor, beta subunit
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-3
Spacegroup:
P43212
Expression system: Escherichia coli BL21(DE3)
