› 1hc9

X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-219393 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Alpha-bungarotoxin isoform V31 Chain: A
Molecule details ›
Chain: A
Length: 74 amino acids
Theoretical weight: 8.03 KDa
Source organism: Bungarus multicinctus
UniProt:
  • Canonical: P60616 (Residues: 22-95; Coverage: 100%)
Structure domains: CD59
Alpha-bungarotoxin Chain: B
Molecule details ›
Chain: B
Length: 74 amino acids
Theoretical weight: 8.01 KDa
Source organism: Bungarus multicinctus
UniProt:
  • Canonical: P60615 (Residues: 22-95; Coverage: 100%)
Structure domains: CD59
PEPTIDE INHIBITOR Chains: C, D
Molecule details ›
Chains: C, D
Length: 13 amino acids
Theoretical weight: 1.69 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand IOD 2 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 42.042Å b: 153.356Å c: 73.263Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 0.235
Expression system: Not provided

Quick links

Citations

20 review citations

Emerging structure of the nicotinic acetylcholine receptors.
Karlin A. (2002)
19 more

7 mentions without citation

Evolution and Medical Significance of LU Domain-Containing Proteins.
Leth et al. (2019)
6 more