1hdm

X-ray diffraction
2.5Å resolution

HISTOCOMPATIBILITY ANTIGEN HLA-DM

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
PDBe Complex ID:
PDB-CPX-151165 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
HLA class II histocompatibility antigen, DM alpha chain Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.86 KDa
Source organism: Homo sapiens
Expression system: Drosophila hydei
UniProt:
  • Canonical: P28067 (Residues: 27-230; Coverage: 86%)
Gene names: DMA, HLA-DMA, RING6
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DM beta chain Chain: B
Molecule details ›
Chain: B
Length: 193 amino acids
Theoretical weight: 21.61 KDa
Source organism: Homo sapiens
Expression system: Drosophila hydei
UniProt:
  • Canonical: P28068 (Residues: 19-218; Coverage: 79%)
Gene names: DMB, HLA-DMB, RING7
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2221
Unit cell:
a: 95.39Å b: 109.93Å c: 105.12Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.257
Expression system: Drosophila hydei