› 1he9

X-ray diffraction
2.4Å resolution

Crystal structure of the GAP domain of the Pseudomonas aeruginosa ExoS toxin

Released:
DOI: 10.2210/pdb1he9/pdb
PDB entry 1he9 coloured by chain, front view.
PDB entry 1he9 coloured by chain, side view.
PDB entry 1he9 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Structure of the ExoS GTPase activating domain.
Würtele M, Renault L, Barbieri JT, Wittinghofer A, Wolf E
FEBS Lett 491 26-9 (2001)
PMID: 11226412

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175940 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exoenzyme S Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 14.43 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q51451 (Residues: 102-234; Coverage: 29%)
Gene name: exoS
Sequence domains: Yersinia virulence determinant (YopE)
Structure domains: Virulence factor YopE uncharacterised domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2221
Unit cell:
a: 42.897Å b: 55.646Å c: 107.472Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.257 0.257 0.265
Expression system: Escherichia coli

Quick links

Citations

8 review citations

The type III secretion system of Pseudomonas aeruginosa: infection by injection.
Hauser AR. (2009)
7 more

5 mentions without citation

Protein-protein docking benchmark version 3.0.
Hwang et al. (2008)
4 more