› 1hfz

X-ray diffraction
2.3Å resolution

Function and Biology Details

Reaction catalysed: 
UDP-alpha-D-galactose + D-glucose = UDP + lactose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132933 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-lactalbumin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 124 amino acids
Theoretical weight: 14.3 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00711 (Residues: 20-142; Coverage: 100%)
Gene names: ALACTA, LALBA
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 58.62Å b: 60.13Å c: 77.18Å
α: 90° β: 96.85° γ: 90°
R-values:
R R work R free
0.208 0.208 0.303
Expression system: Escherichia coli

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Citations

8 review citations

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase.
Jurneczko et al. (2011)
7 more

17 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
16 more