› 1hio

X-ray diffraction
3.1Å resolution

HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN, ALPHA CARBONS ONLY

Released:
DOI: 10.2210/pdb1hio/pdb
PDB entry 1hio coloured by chain, front view.
PDB entry 1hio coloured by chain, side view.
PDB entry 1hio coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix.
Arents G, Burlingame RW, Wang BC, Love WE, Moudrianakis EN
Proc Natl Acad Sci U S A 88 10148-52 (1991)
PMID: 1946434

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135435 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Histone H2A-IV Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.4 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P02263 (Residues: 16-110; Coverage: 74%)
Sequence domains:
Histone H2B 7 Chain: B
Molecule details ›
Chain: B
Length: 90 amino acids
Theoretical weight: 9.91 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P0C1H5 (Residues: 37-126; Coverage: 71%)
Gene name: H2B-VII
Sequence domains: Core histone H2A/H2B/H3/H4
Histone H3.2 Chain: C
Molecule details ›
Chain: C
Length: 93 amino acids
Theoretical weight: 10.78 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P84229 (Residues: 44-136; Coverage: 68%)
Gene names: H3-I, H3-II, H3-III, H3-IV, H3-V, H3-VI, H3-VII, H3-VIII
Sequence domains: Core histone H2A/H2B/H3/H4
Histone H4 Chain: D
Molecule details ›
Chain: D
Length: 76 amino acids
Theoretical weight: 8.57 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P62801 (Residues: 28-103; Coverage: 74%)
Gene names: H4-I, H4-II, H4-III, H4-IV, H4-V, H4-VI, H4-VII
Sequence domains: Centromere kinetochore component CENP-T histone fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 118.82Å b: 118.82Å c: 102.93Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.255 not available not available

Quick links

Citations

111 review citations

Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome.
Kornberg et al. (1999)
110 more

3 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
2 more