1hjx

X-ray diffraction
1.85Å resolution

Ligand-induced signalling and conformational change of the 39 kD glycoprotein from human articular chondrocytes

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-153159 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Chitinase-3-like protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 362 amino acids
Theoretical weight: 40.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P36222 (Residues: 22-383; Coverage: 100%)
Gene name: CHI3L1
Sequence domains: Glycosyl hydrolases family 18
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 109.562Å b: 122.048Å c: 136.097Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.225