› 1hr2

X-ray diffraction
2.25Å resolution

CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.

Released:
DOI: 10.2210/pdb1hr2/pdb
PDB entry 1hr2 coloured by chain, front view.
PDB entry 1hr2 coloured by chain, side view.
PDB entry 1hr2 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Juneau K, Podell E, Harrington DJ, Cech TR
Structure 9 221-31 (2001)
PMID: 11286889

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196039 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN Chains: A, B
Molecule details ›
Chains: A, B
Length: 158 nucleotides
Theoretical weight: 51.09 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 42 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 75.3Å b: 125.4Å c: 145.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.244 0.264
Expression system: Not provided

Quick links

Citations

11 review citations

The chemical repertoire of natural ribozymes.
Doudna et al. (2002)
10 more

45 mentions without citation

RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.
Šponer et al. (2018)
44 more