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Solution NMR

SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4

Released:
DOI: 10.2210/pdb1hre/pdb
PDB entry 1hre coloured by chain, front view.
PDB entry 1hre coloured by chain, side view.
PDB entry 1hre coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4.
Nagata K, Kohda D, Hatanaka H, Ichikawa S, Matsuda S, Yamamoto T, Suzuki A, Inagaki F
EMBO J 13 3517-23 (1994)
PMID: 8062828

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169705 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuregulin-1 Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q02297 (Residues: 175-241; Coverage: 11%)
Gene names: GGF, HGL, HRGA, NDF, NRG1, SMDF
Sequence domains: EGF-like domain
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

5 review citations

ARIA: a neuromuscular junction neuregulin.
Fischbach et al. (1997)
4 more

4 mentions without citation

Structure-based view of epidermal growth factor receptor regulation.
Ferguson KM. (2008)
3 more