› 1hsq

Solution NMR

SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA

Released:
DOI: 10.2210/pdb1hsq/pdb
PDB entry 1hsq coloured by chain, front view.
PDB entry 1hsq coloured by chain, side view.
PDB entry 1hsq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the SH3 domain of phospholipase C-gamma.
Kohda D, Hatanaka H, Odaka M, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F
Cell 72 953-60 (1993)
PMID: 7681365

Function and Biology Details

Reaction catalysed: 
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148516 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 8.25 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P19174 (Residues: 790-852; Coverage: 5%)
Gene names: PLC1, PLCG1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

15 review citations

Protein-protein interactions: methods for detection and analysis.
Phizicky et al. (1995)
14 more

4 mentions without citation

Human cancer protein-protein interaction network: a structural perspective.
Kar et al. (2009)
3 more