› 1i07

X-ray diffraction
1.8Å resolution

EPS8 SH3 DOMAIN INTERTWINED DIMER

Released:
DOI: 10.2210/pdb1i07/pdb
PDB entry 1i07 coloured by chain, front view.
PDB entry 1i07 coloured by chain, side view.
PDB entry 1i07 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Kishan KV, Newcomer ME, Rhodes TH, Guilliot SD
Protein Sci 10 1046-55 (2001)
PMID: 11316885

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170660 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor kinase substrate 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 60 amino acids
Theoretical weight: 7.04 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08509 (Residues: 532-591; Coverage: 7%)
Gene name: Eps8
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P1
Unit cell:
a: 27.899Å b: 28.517Å c: 37.188Å
α: 107.39° β: 96.87° γ: 104.56°
R-values:
R R work R free
0.202 0.202 0.233
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Signal transduction in bacterial chemotaxis.
Baker et al. (2006)
6 more

5 mentions without citation

Domain swapping is a consequence of minimal frustration.
Yang et al. (2004)
4 more