1igt

X-ray diffraction
2.8Å resolution

STRUCTURE OF IMMUNOGLOBULIN

Released:
Source organism: Mus musculus
Primary publication:
Refined structure of an intact IgG2a monoclonal antibody.
Biochemistry 36 1581-97 (1997)
PMID: 9048542

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-224990 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
IGG2A INTACT ANTIBODY - MAB231 Chains: A, C
Molecule details ›
Chains: A, C
Length: 214 amino acids
Theoretical weight: 23.42 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Ig gamma-2A chain C region, A allele Chains: B, D
Molecule details ›
Chains: B, D
Length: 444 amino acids
Theoretical weight: 49.29 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01863 (Residues: 1-326; Coverage: 99%)
Gene name: Ighg
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, GAL, FUL
Carbohydrate polymer : NEW Components: NAG, BMA, MAN, GAL, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P1
Unit cell:
a: 65.82Å b: 76.77Å c: 100.64Å
α: 88.05° β: 92.35° γ: 97.23°
R-values:
R R work R free
0.209 0.209 0.297