› 1ilt

X-ray diffraction
2Å resolution

X-RAY STRUCTURE OF INTERLEUKIN-1 RECEPTOR ANTAGONIST AT 2.0 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1ilt/pdb
PDB entry 1ilt coloured by chain, front view.
PDB entry 1ilt coloured by chain, side view.
PDB entry 1ilt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution.
Vigers GP, Caffes P, Evans RJ, Thompson RC, Eisenberg SP, Brandhuber BJ
J Biol Chem 269 12874-9 (1994)
PMID: 8175703

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148399 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 receptor antagonist protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 17.15 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P18510 (Residues: 26-177; Coverage: 100%)
Gene names: IL1F3, IL1RA, IL1RN
Sequence domains: Interleukin-1 / 18

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 71.11Å b: 71.11Å c: 112.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.236 not available
Expression system: Not provided

Quick links

Citations

11 review citations

Interleukin-1 receptor antagonist: role in biology.
Arend et al. (1998)
10 more