› 1iq3

Solution NMR

SOLUTION STRUCTURE OF THE EPS15 HOMOLOGY DOMAIN OF A HUMAN POB1

Released:
DOI: 10.2210/pdb1iq3/pdb
PDB entry 1iq3 coloured by chain, ensemble of 18 models, front view.
PDB entry 1iq3 coloured by chain, ensemble of 18 models, side view.
PDB entry 1iq3 coloured by chain, ensemble of 18 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1).
Koshiba S, Kigawa T, Iwahara J, Kikuchi A, Yokoyama S
FEBS Lett 442 138-42 (1999)
PMID: 9928989

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185530 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RalBP1-associated Eps domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8NFH8 (Residues: 265-369; Coverage: 16%)
Gene names: POB1, REPS2
Sequence domains: Cytoskeletal-regulatory complex EF hand
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

Quick links

Citations

7 review citations

The EH network.
Santolini et al. (1999)
6 more

4 mentions without citation

Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.
Wang et al. (2006)
3 more