› 1ixa

Solution NMR

THE THREE-DIMENSIONAL STRUCTURE OF THE FIRST EGF-LIKE MODULE OF HUMAN FACTOR IX: COMPARISON WITH EGF AND TGF-A

Released:
DOI: 10.2210/pdb1ixa/pdb
PDB entry 1ixa coloured by chain, front view.
PDB entry 1ixa coloured by chain, side view.
PDB entry 1ixa coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha.
Baron M, Norman DG, Harvey TS, Handford PA, Mayhew M, Tse AG, Brownlee GG, Campbell ID
Protein Sci 1 81-90 (1992)
PMID: 1304885

Function and Biology Details

Reaction catalysed: 
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133190 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coagulation factor IXa light chain Chain: A
Molecule details ›
Chain: A
Length: 39 amino acids
Theoretical weight: 4.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P00740 (Residues: 92-130; Coverage: 9%)
Gene name: F9
Sequence domains: EGF-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

3 review citations

Thrombospondins: multifunctional regulators of cell interactions.
Adams JC. (2001)
2 more

4 mentions without citation

Universality classes in folding times of proteins.
Cieplak et al. (2003)
3 more