Function and Biology Details
Reaction catalysed:
Guanine(15) in tRNA + 7-cyano-7-carbaguanine = 7-cyano-7-carbaguanine(15) in tRNA + guanine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
tRNA-guanine(15) transglycosylase and RNA (preferred)
PDBe Complex ID:
PDB-CPX-129777 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
tRNA-guanine(15) transglycosylase
Molecule details ›
Chains: A, B
Length: 582 amino acids
Theoretical weight: 66.7 KDa
Source organism: Pyrococcus horikoshii
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 582 amino acids
Theoretical weight: 66.7 KDa
Source organism: Pyrococcus horikoshii
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O58843 (Residues: 1-582; Coverage: 100%)
Sequence domains:
- Queuine tRNA-ribosyltransferase
- C1 domain of tRNA-guanine transglycosylase dimerisation
- Patch-forming domain C2 of tRNA-guanine transglycosylase
- PUA domain
