› 1j6z

X-ray diffraction
1.54Å resolution

UNCOMPLEXED ACTIN

Released:
DOI: 10.2210/pdb1j6z/pdb
PDB entry 1j6z coloured by chain, front view.
PDB entry 1j6z coloured by chain, side view.
PDB entry 1j6z coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
The crystal structure of uncomplexed actin in the ADP state.
Otterbein LR, Graceffa P, Dominguez R
Science 293 708-11 (2001)
PMID: 11474115

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159302 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand CA 6 x CA
Ligand ADP 1 x ADP
Ligand RHO 1 x RHO
1 modified residue:
Ligand HIC 1 x HIC

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C, APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 112.808Å b: 37.498Å c: 85.261Å
α: 90° β: 108.26° γ: 90°
R-values:
R R work R free
0.179 0.179 0.223

Quick links

Citations

36 review citations

Mechanism and function of formins in the control of actin assembly.
Goode et al. (2007)
35 more

93 mentions without citation

Actin structure and function.
Dominguez et al. (2011)
92 more