› 1j87

X-ray diffraction
3.2Å resolution

HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1

Released:
DOI: 10.2210/pdb1j87/pdb
PDB entry 1j87 coloured by chain, front view.
PDB entry 1j87 coloured by chain, side view.
PDB entry 1j87 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
Garman SC, Sechi S, Kinet JP, Jardetzky TS
J Mol Biol 311 1049-62 (2001)
PMID: 11531339

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146140 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
High affinity immunoglobulin epsilon receptor subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 19.94 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P12319 (Residues: 26-197; Coverage: 74%)
Gene names: FCE1A, FCER1A
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B
Spacegroup: P6122
Unit cell:
a: 58.68Å b: 58.68Å c: 229.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.264 0.264 0.306
Expression system: Spodoptera frugiperda

Quick links

Citations

14 review citations

IgE in allergy and asthma today.
Gould et al. (2008)
13 more