› 1jc5

X-ray diffraction
2.2Å resolution

Function and Biology Details

Reaction catalysed: 
(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186617 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VOC domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 148 amino acids
Theoretical weight: 16.74 KDa
Source organism: Propionibacterium freudenreichii subsp. shermanii
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8VQN0 (Residues: 1-148; Coverage: 100%)
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

1 bound ligand:
Ligand SO4 10 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 55.985Å b: 114.02Å c: 156.418Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.248 0.293
Expression system: Escherichia coli BL21

Quick links

Citations

4 review citations

The ins and outs of ring-cleaving dioxygenases.
Vaillancourt et al. (2006)
3 more

5 mentions without citation

Functional annotation by identification of local surface similarities: a novel tool for structural genomics.
Ferrè et al. (2005)
4 more