› 1jh5

X-ray diffraction
3Å resolution

Crystal Structure of sTALL-1 of TNF family ligand

Released:
DOI: 10.2210/pdb1jh5/pdb
PDB entry 1jh5 coloured by chain, front view.
PDB entry 1jh5 coloured by chain, side view.
PDB entry 1jh5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.
Liu Y, Xu L, Opalka N, Kappler J, Shu HB, Zhang G
Cell 108 383-94 (2002)
PMID: 11853672

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor ligand superfamily member 13b, soluble form Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 144 amino acids
Theoretical weight: 16.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y275 (Residues: 142-285; Coverage: 51%)
Gene names: BAFF, BLYS, TALL1, TNFSF13B, TNFSF20, UNQ401/PRO738, ZTNF4
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6322
Unit cell:
a: 234.242Å b: 234.242Å c: 212.55Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.236 0.252
Expression system: Escherichia coli

Quick links

Citations

46 review citations

BAFF AND APRIL: a tutorial on B cell survival.
Mackay et al. (2003)
45 more

3 mentions without citation

A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Gorelik et al. (2018)
2 more