› 1jnp

X-ray diffraction
2.5Å resolution

Crystal Structure of Murine Tcl1 at 2.5 Resolution

Released:
DOI: 10.2210/pdb1jnp/pdb
PDB entry 1jnp coloured by chain, front view.
PDB entry 1jnp coloured by chain, side view.
PDB entry 1jnp coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of murine Tcl1 at 2.5 A resolution and implications for the TCL oncogene family.
Petock JM, Torshin IY, Wang YF, Du Bois GC, Croce CM, Harrison RW, Weber IT
Acta Crystallogr D Biol Crystallogr 57 1545-51 (2001)
PMID: 11679718

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157458 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell leukemia/lymphoma protein 1A Chains: A, B
Molecule details ›
Chains: A, B
Length: 116 amino acids
Theoretical weight: 14.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P56280 (Residues: 1-116; Coverage: 100%)
Gene names: Tcl1, Tcl1a
Sequence domains: TCL1/MTCP1 family
Structure domains: TCL1/MTCP1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: C2
Unit cell:
a: 89.323Å b: 115.911Å c: 37.945Å
α: 90° β: 115.15° γ: 90°
R-values:
R R work R free
0.196 0.226 0.236
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The TCL1 family of oncoproteins: co-activators of transformation.
Teitell MA. (2005)
3 more