Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132604 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Adapter molecule crk
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 109 amino acids
Theoretical weight: 12.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P46108 (Residues: 12-120; Coverage: 36%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Adapter molecule crk
Molecule details ›
Chain: B
Length: 13 amino acids
Theoretical weight: 1.47 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
Length: 13 amino acids
Theoretical weight: 1.47 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
- Canonical: Q64010 (Residues: 217-228; Coverage: 4%)
Tyrosine-protein kinase ABL1
Molecule details ›
Chain: C
Length: 61 amino acids
Theoretical weight: 6.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 61 amino acids
Theoretical weight: 6.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P00519 (Residues: 62-122; Coverage: 5%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
