› 1jwf

X-ray diffraction
2.1Å resolution

Crystal Structure of human GGA1 VHS domain.

Released:
DOI: 10.2210/pdb1jwf/pdb
PDB entry 1jwf coloured by chain, front view.
PDB entry 1jwf coloured by chain, side view.
PDB entry 1jwf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for recognition of acidic-cluster dileucine sequence by GGA1.
Shiba T, Takatsu H, Nogi T, Matsugaki N, Kawasaki M, Igarashi N, Suzuki M, Kato R, Earnest T, Nakayama K, Wakatsuki S
Nature 415 937-41 (2002)
PMID: 11859376

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193827 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor-binding protein GGA1 Chain: A
Molecule details ›
Chain: A
Length: 147 amino acids
Theoretical weight: 16.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJY5 (Residues: 1-147; Coverage: 23%)
Gene name: GGA1
Sequence domains: VHS domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B
Spacegroup: P43212
Unit cell:
a: 55.12Å b: 55.12Å c: 105.513Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.222 0.261
Expression system: Escherichia coli

Quick links

Citations

28 review citations

Signals for sorting of transmembrane proteins to endosomes and lysosomes.
Bonifacino et al. (2003)
27 more

6 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
5 more