Assemblies
Multimeric state:
hetero tetramer
Accessible surface area:
28005.93 Å2
Buried surface area:
8856.05 Å2
Dissociation area:
694.75
Å2
Dissociation energy (ΔGdiss):
-2.85
kcal/mol
Dissociation entropy (TΔSdiss):
13.03
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-135330
Macromolecules
Chain: A
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
SCOP:
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01903 (Residues: 26-207; Coverage: 80%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- MHC class II, alpha chain, N-terminal
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
SCOP:
Chain: B
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
SCOP:
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01911 (Residues: 30-219; Coverage: 80%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
- MHC class II, beta chain, N-terminal
SCOP:
Chain: D
Length: 239 amino acids
Theoretical weight: 27.66 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
Pfam:
SCOP:
Length: 239 amino acids
Theoretical weight: 27.66 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
- Canonical: P0A0L5 (Residues: 28-266; Coverage: 100%)
Pfam:
- Staphylococcal/Streptococcal toxin, OB-fold domain
- Staphylococcal/Streptococcal toxin, beta-grasp domain
- Enterotoxin
- Staphylococcal/Streptococcal toxin, OB-fold
- Superantigen, staphylococcal/streptococcal toxin, bacterial
- Staphylococcal/streptococcal toxin, bacterial
- Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site
- Superantigen toxin, C-terminal
- Staphylococcal/Streptococcal toxin, beta-grasp domain
SCOP: