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Solution NMR

Homonuclear 1H Nuclear Magnetic Resonance Assignment and Structural Characterization of HIV-1 Tat Mal Protein

Released:
DOI: 10.2210/pdb1k5k/pdb
PDB entry 1k5k coloured by chain, ensemble of 10 models, front view.
PDB entry 1k5k coloured by chain, ensemble of 10 models, side view.
PDB entry 1k5k coloured by chain, ensemble of 10 models, top view.
Source organism: Human immunodeficiency virus type 1 (MAL ISOLATE)
Primary publication:
Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein.
Grégoire C, Péloponèse JM, Esquieu D, Opi S, Campbell G, Solomiac M, Lebrun E, Lebreton J, Loret EP
Biopolymers 62 324-35 (2001)
PMID: 11857271

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein Tat Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 10.06 KDa
Source organism: Human immunodeficiency virus type 1 (MAL ISOLATE)
Expression system: Not provided
UniProt:
  • Canonical: P04613 (Residues: 1-87; Coverage: 100%)
Gene name: tat
Sequence domains: Transactivating regulatory protein (Tat)
Structure domains: Tat domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Not provided

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Citations

8 review citations

Role of Tat protein in HIV neuropathogenesis.
Li et al. (2009)
7 more

5 mentions without citation

How random are intrinsically disordered proteins? A small angle scattering perspective.
Receveur-Brechot et al. (2012)
4 more