› 1kbs

Solution NMR

SOLUTION STRUCTURE OF CARDIOTOXIN IV, NMR, 1 STRUCTURE

Released:
DOI: 10.2210/pdb1kbs/pdb
PDB entry 1kbs coloured by chain, front view.
PDB entry 1kbs coloured by chain, side view.
PDB entry 1kbs coloured by chain, top view.
Source organism: Naja atra
Primary publication:
Comparison of the hemolytic activity and solution structures of two snake venom cardiotoxin analogues which only differ in their N-terminal amino acid.
Jang JY, Krishnaswamy T, Kumar S, Jayaraman G, Yang PW, Yu C
Biochemistry 36 14635-41 (1997)
PMID: 9398182

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134315 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxin 4 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.8 KDa
Source organism: Naja atra
UniProt:
  • Canonical: P01443 (Residues: 22-81; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores

Quick links

Citations

1 review citation

The role of hydrophobic /hydrophilic balance in the activity of structurally flexible vs. rigid cytolytic polypeptides and analogs developed on their basis.
Dubovskii et al. (2018)
15 other articles

1 mention without citation

Cobra cytotoxins: structural organization and antibacterial activity.
Dubovskii et al. (2014)