Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu
- DNA polymerase family X
- Nucleotidyltransferase superfamily
- DNA-directed DNA polymerase X
- DNA polymerase lambda lyase domain superfamily
- DNA polymerase beta, thumb domain
- DNA polymerase, thumb domain superfamily
- DNA polymerase family X, binding site
3 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
DNA nucleotidylexotransferase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-114077 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
DNA nucleotidylexotransferase
Molecule details ›
Chain: A
Length: 363 amino acids
Theoretical weight: 41.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 363 amino acids
Theoretical weight: 41.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P09838 (Residues: 148-510; Coverage: 71%)
Sequence domains:
- Helix-hairpin-helix domain
- Fingers domain of DNA polymerase lambda
- Nucleotidyltransferase domain
- DNA polymerase beta thumb
