Assemblies
Multimeric state:
hetero tetramer
Accessible surface area:
25035.61 Å2
Buried surface area:
8407.68 Å2
Dissociation area:
513.11
Å2
Dissociation energy (ΔGdiss):
-9.03
kcal/mol
Dissociation entropy (TΔSdiss):
12.13
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-135315
Macromolecules
Chain: A
Length: 180 amino acids
Theoretical weight: 20.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
SCOP:
Length: 180 amino acids
Theoretical weight: 20.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01903 (Residues: 28-207; Coverage: 79%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC class II, alpha chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
SCOP:
Chain: B
Length: 188 amino acids
Theoretical weight: 21.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
SCOP:
Length: 188 amino acids
Theoretical weight: 21.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01911 (Residues: 32-219; Coverage: 79%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
- MHC class II, beta chain, N-terminal
SCOP:
Chain: D
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
- Canonical: P03437 (Residues: 322-334; Coverage: 2%)
Chain: C
Length: 136 amino acids
Theoretical weight: 15.63 KDa
Source organism: human gammaherpesvirus 4
Expression system: Trichoplusia ni
UniProt:
InterPro:
CATH: Mannose-Binding Protein A, subunit A
SCOP: C-type lectin domain
Length: 136 amino acids
Theoretical weight: 15.63 KDa
Source organism: human gammaherpesvirus 4
Expression system: Trichoplusia ni
UniProt:
- Canonical: P03205 (Residues: 86-221; Coverage: 61%)
InterPro:
CATH: Mannose-Binding Protein A, subunit A
SCOP: C-type lectin domain