› 1klp

Solution NMR

The Solution Structure of Acyl Carrier Protein from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb1klp/pdb
PDB entry 1klp coloured by chain, ensemble of 20 models, front view.
PDB entry 1klp coloured by chain, ensemble of 20 models, side view.
PDB entry 1klp coloured by chain, ensemble of 20 models, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
The solution structure of acyl carrier protein from Mycobacterium tuberculosis.
Wong HC, Liu G, Zhang YM, Rock CO, Zheng J
J Biol Chem 277 15874-80 (2002)
PMID: 11825906

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162072 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Meromycolate extension acyl carrier protein Chain: A
Molecule details ›
Chain: A
Length: 115 amino acids
Theoretical weight: 12.53 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WQF3 (Residues: 1-115; Coverage: 100%)
Gene names: MTCY427.25, Rv2244, acpM
Sequence domains: Phosphopantetheine attachment site
Structure domains: ACP-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics simulated annealing
Expression system: Escherichia coli

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Citations

13 review citations

Biosynthesis of nonribosomal peptides1.
Finking et al. (2004)
12 more

11 mentions without citation

Solution NMR Studies of Mycobacterium tuberculosis Proteins for Antibiotic Target Discovery.
Kim et al. (2017)
10 more