› 1kma

Solution NMR

NMR Structure of the Domain-I of the Kazal-type Thrombin Inhibitor Dipetalin

Released:
DOI: 10.2210/pdb1kma/pdb
PDB entry 1kma coloured by chain, ensemble of 20 models, front view.
PDB entry 1kma coloured by chain, ensemble of 20 models, side view.
PDB entry 1kma coloured by chain, ensemble of 20 models, top view.
Source organism: Dipetalogaster maximus
Primary publication:
Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies.
Schlott B, Wöhnert J, Icke C, Hartmann M, Ramachandran R, Gührs KH, Glusa E, Flemming J, Görlach M, Grosse F, Ohlenschläger O
J Mol Biol 318 533-46 (2002)
PMID: 12051857

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease inhibitor dipetalogastin Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.09 KDa
Source organism: Dipetalogaster maximus
Expression system: Escherichia coli
UniProt:
  • Canonical: O96790 (Residues: 132-186; Coverage: 16%)
Sequence domains: Kazal-type serine protease inhibitor domain
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry/simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structure and function of invertebrate Kazal-type serine proteinase inhibitors.
Rimphanitchayakit et al. (2010)
3 more

4 mentions without citation

Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission.
Blisnick et al. (2017)
3 more