› 1kmg

Solution NMR

The Solution Structure Of Monomeric Copper-free Superoxide Dismutase

Released:
DOI: 10.2210/pdb1kmg/pdb
PDB entry 1kmg coloured by chain, ensemble of 35 models, front view.
PDB entry 1kmg coloured by chain, ensemble of 35 models, side view.
PDB entry 1kmg coloured by chain, ensemble of 35 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and dynamics of copper-free SOD: The protein before binding copper.
Banci L, Bertini I, Cantini F, D'Onofrio M, Viezzoli MS
Protein Sci 11 2479-92 (2002)
PMID: 12237469

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 15.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

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Citations

5 review citations

Copper metallochaperones.
Robinson et al. (2010)
4 more

5 mentions without citation

Posttranslational modifications in Cu,Zn-superoxide dismutase and mutations associated with amyotrophic lateral sclerosis.
Furukawa et al. (2006)
4 more