› 1knw

X-ray diffraction
2.1Å resolution

Crystal structure of diaminopimelate decarboxylase

Released:
DOI: 10.2210/pdb1knw/pdb
PDB entry 1knw coloured by chain, front view.
PDB entry 1knw coloured by chain, side view.
PDB entry 1knw coloured by chain, top view.
Source organism: Escherichia coli
Entry authors: Levdikov V, Blagova L, Bose N, Momany C

Function and Biology Details

Reaction catalysed: 
Meso-2,6-diaminoheptanedioate = L-lysine + CO(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133644 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Diaminopimelate decarboxylase Chain: A
Molecule details ›
Chain: A
Length: 425 amino acids
Theoretical weight: 46.92 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00861 (Residues: 1-420; Coverage: 100%)
Gene names: JW2806, b2838, lysA
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand PLP 1 x PLP
3 bound ligands:
Ligand SO4 1 x SO4
Ligand LI 2 x LI
Ligand MES 1 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6122
Unit cell:
a: 98.58Å b: 98.58Å c: 176.95Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.173 0.22
Expression system: Escherichia coli BL21(DE3)

Quick links