› 1kxi

X-ray diffraction
2.19Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158613 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxin A5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 62 amino acids
Theoretical weight: 7.03 KDa
Source organism: Naja atra
Expression system: Escherichia coli
UniProt:
  • Canonical: P62375 (Residues: 22-83; Coverage: 100%)
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P41212
Unit cell:
a: 43.3Å b: 43.3Å c: 147.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.207 0.305
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The role of hydrophobic /hydrophilic balance in the activity of structurally flexible vs. rigid cytolytic polypeptides and analogs developed on their basis.
Dubovskii et al. (2018)
23 other articles

6 mentions without citation

Benchmarking pK(a) prediction.
Davies et al. (2006)
5 more