› 1l1j

X-ray diffraction
2.8Å resolution

Crystal structure of the protease domain of an ATP-independent heat shock protease HtrA

Released:
DOI: 10.2210/pdb1l1j/pdb
PDB entry 1l1j coloured by chain, front view.
PDB entry 1l1j coloured by chain, side view.
PDB entry 1l1j coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Crystal structure of the protease domain of a heat-shock protein HtrA from Thermotoga maritima.
Kim DY, Kim DR, Ha SC, Lokanath NK, Lee CJ, Hwang HY, Kim KK
J Biol Chem 278 6543-51 (2003)
PMID: 12458220

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194573 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PDZ domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 239 amino acids
Theoretical weight: 25.93 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WZ41 (Residues: 24-262; Coverage: 55%)
Gene name: TM_0571
Sequence domains: Trypsin-like peptidase domain
Structure domains: Trypsin-like serine proteases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P213
Unit cell:
a: 120.55Å b: 120.55Å c: 120.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.278
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The mitochondrial serine protease HtrA2/Omi: an overview.
Vande Walle et al. (2008)
5 more

4 mentions without citation

Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress.
Biswas et al. (2010)
3 more