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Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine

Source organism: Geobacillus stearothermophilus
Biochemical function: pyridoxal phosphate binding
Biological process: D-alanine biosynthetic process
Cellular component: cytosol

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EC 5.1.1.1: Alanine racemase

Reaction catalysed:
L-alanine = D-alanine
Systematic name:
Alanine racemase
Alternative Name(s):
  • L-alanine racemase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00842
Domain description: Alanine racemase, C-terminal domain
Occurring in:
  1. Alanine racemase
The deposited structure of PDB entry 1l6g contains 2 copies of Pfam domain PF00842 (Alanine racemase, C-terminal domain) in Alanine racemase. Showing 1 copy in chain A.

PF01168
Domain description: Alanine racemase, N-terminal domain
Occurring in:
  1. Alanine racemase
The deposited structure of PDB entry 1l6g contains 2 copies of Pfam domain PF01168 (Alanine racemase, N-terminal domain) in Alanine racemase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000821
Domain description: Alanine racemase
Occurring in:
  1. Alanine racemase
IPR011079
Domain description: Alanine racemase, C-terminal
Occurring in:
  1. Alanine racemase
IPR029066
Domain description: PLP-binding barrel
Occurring in:
  1. Alanine racemase
IPR009006
Domain description: Alanine racemase/group IV decarboxylase, C-terminal
Occurring in:
  1. Alanine racemase
IPR020622
Domain description: Alanine racemase, pyridoxal-phosphate attachment site
Occurring in:
  1. Alanine racemase
IPR001608
Domain description: Alanine racemase, N-terminal
Occurring in:
  1. Alanine racemase

Structure domains

CATH CATH domains
2.40.37.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Lyase, Ornithine Decarboxylase; Chain A, domain 1
Homology: Lyase, Ornithine Decarboxylase; Chain A, domain 1
Occurring in:
  1. Alanine racemase
The deposited structure of PDB entry 1l6g contains 2 copies of CATH domain 2.40.37.10 (Lyase, Ornithine Decarboxylase; Chain A, domain 1) in Alanine racemase. Showing 1 copy in chain A.
3.20.20.10
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Alanine racemase
Occurring in:
  1. Alanine racemase
The deposited structure of PDB entry 1l6g contains 2 copies of CATH domain 3.20.20.10 (TIM Barrel) in Alanine racemase. Showing 1 copy in chain A.
SCOP SCOP annotations
88682
Class: All beta proteins
Fold: Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily: Alanine racemase C-terminal domain-like
Occurring in:
  1. Alanine racemase
The deposited structure of PDB entry 1l6g contains 2 copies of SCOP domain 88682 (Alanine racemase) in Alanine racemase. Showing 1 copy in chain A.
51420
Class: Alpha and beta proteins (a/b)
Fold: TIM beta/alpha-barrel
Superfamily: PLP-binding barrel
Occurring in:
  1. Alanine racemase
The deposited structure of PDB entry 1l6g contains 2 copies of SCOP domain 51420 (Alanine racemase-like, N-terminal domain) in Alanine racemase. Showing 1 copy in chain A.

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