› 1lin

X-ray diffraction
2Å resolution

CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:4 COMPLEX)

Released:
DOI: 10.2210/pdb1lin/pdb
PDB entry 1lin coloured by chain, front view.
PDB entry 1lin coloured by chain, side view.
PDB entry 1lin coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Trifluoperazine-induced conformational change in Ca(2+)-calmodulin.
Vandonselaar M, Hickie RA, Quail JW, Delbaere LT
Nat Struct Biol 1 795-801 (1994)
PMID: 7634090

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158581 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P62157 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CAM
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand CA 4 x CA
Ligand TFP 4 x TFP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P3221
Unit cell:
a: 40.66Å b: 40.66Å c: 177.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.22 not available

Quick links

Citations

12 review citations

Novel aspects of calmodulin target recognition and activation.
Vetter et al. (2003)
11 more

20 mentions without citation

Tools and methods for circular dichroism spectroscopy of proteins: a tutorial review.
Miles et al. (2021)
19 more