› 1lm6

X-ray diffraction
1.75Å resolution

Function and Biology Details

Reaction catalysed: 
Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190243 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide deformylase Chain: A
Molecule details ›
Chain: A
Length: 215 amino acids
Theoretical weight: 24.23 KDa
Source organism: Streptococcus pneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9F2F0 (Residues: 1-203; Coverage: 100%)
Gene names: SP_1456, def
Sequence domains: Polypeptide deformylase
Structure domains: Peptide deformylase

Ligands and Environments

2 bound ligands:
Ligand FE 1 x FE
Ligand GOL 1 x GOL
1 modified residue:
Ligand OCS 1 x OCS

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P43
Unit cell:
a: 49.709Å b: 49.709Å c: 91.407Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 0.256
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Investigational antimicrobial agents of 2013.
Pucci et al. (2013)
2 more

2 mentions without citation

Metal utilization in genome-reduced bacteria: Do human mycoplasmas rely on iron?
Perálvarez-Marín et al. (2021)
1 more