› 1lv7

X-ray diffraction
1.5Å resolution

Crystal Structure of the AAA domain of FtsH

Released:
DOI: 10.2210/pdb1lv7/pdb
PDB entry 1lv7 coloured by chain, front view.
PDB entry 1lv7 coloured by chain, side view.
PDB entry 1lv7 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
The crystal structure of the AAA domain of the ATP-dependent protease FtsH of Escherichia coli at 1.5 A resolution.
Krzywda S, Brzozowski AM, Verma C, Karata K, Ogura T, Wilkinson AJ
Structure 10 1073-83 (2002)
PMID: 12176385

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-141984 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent zinc metalloprotease FtsH Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 27.77 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0AAI3 (Residues: 141-397; Coverage: 40%)
Gene names: JW3145, b3178, ftsH, hflB, mrsC, std, tolZ
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P41212
Unit cell:
a: 53.152Å b: 53.152Å c: 189.066Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.154 0.178
Expression system: Escherichia coli BL21

Quick links

Citations

20 review citations

Evolutionary relationships and structural mechanisms of AAA+ proteins.
Erzberger et al. (2006)
19 more

10 mentions without citation

Glycines: role in α-helical membrane protein structures and a potential indicator of native conformation.
Dong et al. (2012)
9 more