› 1lwm

Solution NMR

Solution Structure of the Sequence-Non-Specific HMGB protein NHP6A

Released:
DOI: 10.2210/pdb1lwm/pdb
PDB entry 1lwm coloured by chain, ensemble of 20 models, front view.
PDB entry 1lwm coloured by chain, ensemble of 20 models, side view.
PDB entry 1lwm coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding.
Masse JE, Wong B, Yen YM, Allain FH, Johnson RC, Feigon J
J Mol Biol 323 263-84 (2002)
PMID: 12381320

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145886 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-histone chromosomal protein 6A Chain: A
Molecule details ›
Chain: A
Length: 93 amino acids
Theoretical weight: 10.82 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P11632 (Residues: 1-93; Coverage: 100%)
Gene names: NHP6A, NHPA, YP9499.09C, YPR052C
Sequence domains: HMG (high mobility group) box
Structure domains: High mobility group box domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

12 review citations

HMGB proteins and gene expression.
Agresti et al. (2003)
11 more

8 mentions without citation

The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization.
Winkler et al. (2011)
7 more