Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Integrin alphaIIb-beta3 complex (preferred)
PDBe Complex ID:
PDB-CPX-138441 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-IIb light chain, form 2
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Integrin alpha cytoplasmic region
Length: 20 amino acids
Theoretical weight: 2.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P08514 (Residues: 1020-1039; Coverage: 2%)
Sequence domains: Integrin alpha cytoplasmic region
Integrin beta-3
Molecule details ›
Chain: B
Length: 47 amino acids
Theoretical weight: 5.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Integrin beta cytoplasmic domain
Structure domains: Integrin beta subunit, cytoplasmic domain
Length: 47 amino acids
Theoretical weight: 5.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P05106 (Residues: 742-788; Coverage: 6%)
Sequence domains: Integrin beta cytoplasmic domain
Structure domains: Integrin beta subunit, cytoplasmic domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
