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HUMAN PROTEIN DISULFIDE ISOMERASE, NMR, 40 STRUCTURES

Source organism: Homo sapiens
Biochemical function: protein disulfide isomerase activity
Biological process: not assigned
Cellular component: not assigned

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EC 5.3.4.1: Protein disulfide-isomerase

Reaction catalysed:
Catalyzes the rearrangement of -S-S- bonds in proteins
Systematic name:
Protein disulfide-isomerase
Alternative Name(s):
  • S-S rearrangase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00085
Domain description: Thioredoxin
Occurring in:
  1. Protein disulfide-isomerase
The deposited structure of PDB entry 1mek contains 1 copy of Pfam domain PF00085 (Thioredoxin) in Protein disulfide-isomerase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013766
Domain description: Thioredoxin domain
Occurring in:
  1. Protein disulfide-isomerase
IPR017937
Domain description: Thioredoxin, conserved site
Occurring in:
  1. Protein disulfide-isomerase
IPR005788
Domain description: Protein disulfide-isomerase, thioredoxin-like domain
Occurring in:
  1. Protein disulfide-isomerase
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. Protein disulfide-isomerase

Structure domain

CATH CATH domain
3.40.30.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Glutaredoxin
Homology: Glutaredoxin
Occurring in:
  1. Protein disulfide-isomerase
The deposited structure of PDB entry 1mek contains 1 copy of CATH domain 3.40.30.10 (Glutaredoxin) in Protein disulfide-isomerase. Showing 1 copy in chain A.
SCOP SCOP annotation
52849
Class: Alpha and beta proteins (a/b)
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Occurring in:
  1. Protein disulfide-isomerase
The deposited structure of PDB entry 1mek contains 1 copy of SCOP domain 52849 (PDI-like) in Protein disulfide-isomerase. Showing 1 copy in chain A.

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