› 1mmm

X-ray diffraction
2.2Å resolution

DISTINCT METAL ENVIRONMENT IN IRON-SUBSTITUTED MANGANESE SUPEROXIDE DISMUTASE PROVIDES A STRUCTURAL BASIS OF METAL SPECIFICITY

Released:
DOI: 10.2210/pdb1mmm/pdb
PDB entry 1mmm coloured by chain, front view.
PDB entry 1mmm coloured by chain, side view.
PDB entry 1mmm coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Distinct Metal Environment in Fe-Substituted Manganese Superoxide Dismutase Provides a Structural Basis of Metal Specificity
Edwards RA, Whittaker MM, Whittaker JW, Jameson GB, Baker EN
J. Am. Chem. Soc. 120 9684-9685 (1998)

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132509 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Mn] Chains: A, B
Molecule details ›
Chains: A, B
Length: 205 amino acids
Theoretical weight: 23 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P00448 (Residues: 2-206; Coverage: 100%)
Gene names: JW3879, b3908, sodA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand OH 3 x OH
Ligand FE 2 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 46.19Å b: 89.04Å c: 206.671Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.192 0.231

Quick links

Citations

5 mentions without citation

Superoxide dismutases: ancient enzymes and new insights.
Miller AF. (2012)
4 more