› 1msh

Solution NMR

SOLUTION STRUCTURE OF GRO(SLASH)MELANOMA GROWTH STIMULATORY ACTIVITY DETERMINED BY 1H NMR SPECTROSCOPY

Released:
DOI: 10.2210/pdb1msh/pdb
PDB entry 1msh coloured by chain, ensemble of 30 models, front view.
PDB entry 1msh coloured by chain, ensemble of 30 models, side view.
PDB entry 1msh coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of GRO/melanoma growth stimulatory activity determined by 1H NMR spectroscopy.
Kim KS, Clark-Lewis I, Sykes BD
J Biol Chem 269 32909-15 (1994)
PMID: 7806518

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140615 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth-regulated alpha protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 72 amino acids
Theoretical weight: 7.76 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09341 (Residues: 35-106; Coverage: 99%)
Gene names: CXCL1, GRO, GRO1, GROA, MGSA, SCYB1
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

4 review citations

Structural basis of chemokine receptor function--a model for binding affinity and ligand selectivity.
Rajagopalan et al. (2006)
3 more

2 mentions without citation

Human antimicrobial peptides and proteins.
Wang G. (2014)
1 more