› 1n5u

X-ray diffraction
1.9Å resolution

X-RAY STUDY OF HUMAN SERUM ALBUMIN COMPLEXED WITH HEME

Released:
DOI: 10.2210/pdb1n5u/pdb
PDB entry 1n5u coloured by chain, front view.
PDB entry 1n5u coloured by chain, side view.
PDB entry 1n5u coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The atomic structure of human methemalbumin at 1.9 A.
Wardell M, Wang Z, Ho JX, Robert J, Ruker F, Ruble J, Carter DC
Biochem Biophys Res Commun 291 813-9 (2002)
PMID: 11866438

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chain: A
Molecule details ›
Chain: A
Length: 585 amino acids
Theoretical weight: 66.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02768 (Residues: 25-609; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family
Structure domains: Serum Albumin; Chain A, Domain 1

Ligands and Environments

2 bound ligands:
Ligand MYR 5 x MYR
Ligand HEM 1 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: C2
Unit cell:
a: 183.116Å b: 37.909Å c: 94.832Å
α: 90° β: 105.04° γ: 90°
R-values:
R R work R free
0.235 0.235 0.28

Quick links

Citations

25 review citations

The extraordinary ligand binding properties of human serum albumin.
Fasano et al. (2005)
24 more

56 mentions without citation

Thiol redox biochemistry: insights from computer simulations.
Zeida et al. (2014)
55 more