› 1na3

X-ray diffraction
1.55Å resolution

Design of Stable alpha-Helical Arrays from an Idealized TPR Motif

Released:
DOI: 10.2210/pdb1na3/pdb
PDB entry 1na3 coloured by chain, front view.
PDB entry 1na3 coloured by chain, side view.
PDB entry 1na3 coloured by chain, top view.
Source organism: unidentified
Primary publication:
Design of stable alpha-helical arrays from an idealized TPR motif.
Main ER, Xiong Y, Cocco MJ, D'Andrea L, Regan L
Structure 11 497-508 (2003)
PMID: 12737816

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162338 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
designed protein CTPR2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 91 amino acids
Theoretical weight: 10.35 KDa
Source organism: unidentified
Expression system: Escherichia coli
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

3 bound ligands:
Ligand TRS 1 x TRS
Ligand IPT 2 x IPT
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P212121
Unit cell:
a: 44.986Å b: 54.941Å c: 66.938Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.178 0.207
Expression system: Escherichia coli

Quick links

Citations

20 review citations

Engineering novel binding proteins from nonimmunoglobulin domains.
Binz et al. (2005)
19 more

15 mentions without citation

Achieving reliability and high accuracy in automated protein docking: ClusPro, PIPER, SDU, and stability analysis in CAPRI rounds 13-19.
Kozakov et al. (2010)
14 more