› 1naf

X-ray diffraction
2.8Å resolution

Crystal structure of the human GGA1 GAT domain

Released:
DOI: 10.2210/pdb1naf/pdb
PDB entry 1naf coloured by chain, front view.
PDB entry 1naf coloured by chain, side view.
PDB entry 1naf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs.
Collins BM, Watson PJ, Owen DJ
Dev Cell 4 321-32 (2003)
PMID: 12636914

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193827 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor-binding protein GGA1 Chain: A
Molecule details ›
Chain: A
Length: 158 amino acids
Theoretical weight: 18.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJY5 (Residues: 165-314; Coverage: 24%)
Gene name: GGA1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P63
Unit cell:
a: 82.7Å b: 82.7Å c: 69.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.248 0.248 0.283
Expression system: Escherichia coli

Quick links

Citations

13 review citations

ARF proteins: roles in membrane traffic and beyond.
D'Souza-Schorey et al. (2006)
12 more

3 mentions without citation

Structure of Golgi transport proteins.
Kümmel et al. (2011)
2 more