› 1ncv

Solution NMR

DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES

Released:
DOI: 10.2210/pdb1ncv/pdb
PDB entry 1ncv coloured by chain, ensemble of 7 models, front view.
PDB entry 1ncv coloured by chain, ensemble of 7 models, side view.
PDB entry 1ncv coloured by chain, ensemble of 7 models, top view.
Source organism: Homo sapiens
Primary publication:
Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy.
Meunier S, Bernassau JM, Guillemot JC, Ferrara P, Darbon H
Biochemistry 36 4412-22 (1997)
PMID: 9109648

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160349 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 76 amino acids
Theoretical weight: 8.97 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P80098 (Residues: 24-99; Coverage: 100%)
Gene names: CCL7, MCP3, SCYA6, SCYA7
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY SIMULATED ANNEALING
Expression system: Cricetulus griseus

Quick links

Citations

4 review citations

Monocyte chemoattractant protein-1 (MCP-1): an overview.
Deshmane et al. (2009)
3 more

4 mentions without citation

The marriage of chemokines and galectins as functional heterodimers.
von Hundelshausen et al. (2021)
3 more