› 1ncz

X-ray diffraction
1.8Å resolution

TROPONIN C

Released:
DOI: 10.2210/pdb1ncz/pdb
PDB entry 1ncz coloured by chain, front view.
PDB entry 1ncz coloured by chain, side view.
PDB entry 1ncz coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
X-ray structures of Mn, Cd and Tb metal complexes of troponin C.
Rao ST, Satyshur KA, Greaser ML, Sundaralingam M
Acta Crystallogr D Biol Crystallogr 52 916-22 (1996)
PMID: 15299599

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135940 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Troponin C, skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.26 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P02588 (Residues: 2-163; Coverage: 99%)
Gene name: TNNC2
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand TB 2 x TB
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 66.7Å b: 66.7Å c: 60.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.19 not available

Quick links

Citations

2 review citations

Structural characteristics of protein binding sites for calcium and lanthanide ions.
Pidcock et al. (2001)
1 more

1 mention without citation

Intermolecular And Dynamic Investigation of The Mechanism of Action of Reldesemtiv on Fast Skeletal Muscle Troponin Complex Toward the Treatment of Impaired Muscle Function.
Issahaku et al. (2023)