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Crystal Structure Analysis of N-and C-terminal labeled SH3-domain of alpha-Chicken Spectrin

X-ray diffraction
2.3Å resolution
PDB entry 1neg coloured by chain, front view.
PDB entry 1neg coloured by chain, side view.
PDB entry 1neg coloured by chain, top view.
Source organism: Gallus gallus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Spectrin alpha chain, non-erythrocytic 1
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Multimeric state: monomeric
Accessible surface area: 4708.3 Å2
Buried surface area: 144.12 Å2
Dissociation area: 72.06 Å2
Dissociation energy (ΔGdiss): 1.93 kcal/mol
Dissociation entropy (TΔSdiss): -3.31 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-139741

Macromolecules

Spectrin alpha chain, non-erythrocytic 1
Chain: A
Length: 83 amino acids
Theoretical weight: 9.64 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P07751 (Residues: 965-1029; Coverage: 3%)
Gene names: SPTA2, SPTAN1
Pfam: SH3 domain
InterPro:
CATH: SH3 Domains
SCOP: SH3-domain
Spectrin alpha chain, non-erythrocytic 1 in PDB entry 1neg, assembly 1, front view.
Spectrin alpha chain, non-erythrocytic 1 in PDB entry 1neg, assembly 1, side view.
Spectrin alpha chain, non-erythrocytic 1 in PDB entry 1neg, assembly 1, top view.
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