› 1njn

X-ray diffraction
3.7Å resolution

The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed with the antibiotic sparsomycin

Released:
DOI: 10.2210/pdb1njn/pdb
PDB entry 1njn coloured by chain, front view.
PDB entry 1njn coloured by chain, side view.
PDB entry 1njn coloured by chain, top view.
Source organism: Deinococcus radiodurans
Primary publication:
Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression.
Bashan A, Agmon I, Zarivach R, Schluenzen F, Harms J, Berisio R, Bartels H, Franceschi F, Auerbach T, Hansen HA, Kossoy E, Kessler M, Yonath A
Mol Cell 11 91-102 (2003)
PMID: 12535524

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196140 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
23S ribosomal RNA Chain: 0
Molecule details ›
Chain: 0
Length: 2880 nucleotides
Theoretical weight: 933.41 KDa
Source organism: Deinococcus radiodurans
Sequence domains: Bacterial large subunit ribosomal RNA

Ligands and Environments

1 bound ligand:
Ligand SPS 1 x SPS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: I222
Unit cell:
a: 169.1Å b: 409.9Å c: 696.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.284 0.284 0.308

Quick links

Citations

46 review citations

What recent ribosome structures have revealed about the mechanism of translation.
Schmeing et al. (2009)
45 more

4 mentions without citation

POPSCOMP: an automated interaction analysis of biomolecular complexes.
Kleinjung et al. (2005)
3 more